The capacity of Mycobacterium complex species and M. bovis BCG substrains specific identification – implications for optimized PCR-based diagnostics in adverse events following vaccination suspected cases

Katarzyna Krysztopa-Grzybowska, Sylwia Brzezińska, Ewa Augustynowicz-Kopeć, Zofia Zwolska, Ewa Augustynowicz, Anna Lutyńska
Pol J Microbiol
2012; 61 (4):
ICID: 1031328
Article type: Original article
IC™ Value: 10.00
Abstract provided by Publisher
Three nucleic acid techniques approaches described in the literature as potentially applicable in the diagnostics were tested for its capacity of differentiation of Mycobacterium bovis BCG from other members of M. tuberculosis complex species in samples of mycobacteria grown from individuals suspected of adverse events following BCG vaccination comparing to appropriate reference strains. The goal of this pilot study was the evaluation of their identification capacity for routine confirmation of the mycobacteria species as infection source in the cases of adverse events following BCG vaccination.

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