IS6110-based differentiation of Mycobacterium tuberculosis strains

Anna Żaczek, Małgorzata Ziółkiewicz, Arkadiusz Wojtasik, Jarosław Dziadek, Anna Sajduda
Pol J Microbiol
2013; 62 (2):
ICID: 1055714
Article type: Short communication
IC™ Value: 6.00
Abstract provided by Publisher
In this study, 62 Mycobacterium tuberculosis strains were characterized by fast ligation-mediated PCR (FLiP) and, previously performed, IS6110 restriction fragment length polymorphism (RFLP). FLiP proved a reproducible and specific method for differentiation between M. tuberculosis strains. Discriminatory power of FLiP was close to that of the reference IS6110 RFLP suggesting its usefulness in studying genetic diversity of M. tuberculosis strains.

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