Characteristic of bacteriocines and their application

Tomasz M. KarpiƄski, Anna K. Szkaradkiewicz
Pol J Microbiol
2013; 62 (3):
ICID: 1072787
Article type: Review article
IC™ Value: 8.00
Abstract provided by Publisher
 
Bacteriocines are small peptides manifesting anti-bacterial properties. They are produced both by Gram-positive and Gram-negative bacteria. Until now, a few hundred bacteriocines were described. Classification of bacteriocines undergoes continuous alterations, linked to studies on their structure, amino acid sequence and recognised mechanism of their action. Some of bacteriocins (lantibiotics) contain atypical amino acids, such as lantionine (Lan), methyllantionine (MeLan), dehydroalanine (Dha), dehydrobutyrine (Dhb), or D-alanine (D-Ala). The best recognized bacteriocines are produced by lactic acid bacteria, including nisine produced by strains of Lactococcus lactis. These bacteriocines have been recognized to be fully safe for humans. At present, nisine is used in food industry, as a conserving agent. Other lactic acid bacteria bacteriocines and probiotic preparations provide an alternative for antibiotics, and are used in food and in animal feed.
PMID 24459827 - click here to show this article in PubMed
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