Trends in Antifungal Susceptibility of Candida Species - One Year Observation
Marlena Gołaś, Irena Netsvyetayeva, Magdalena Sikora, Katarzyna Piskorska, Beata Sulik-Tyszka, Ewa Swoboda-Kopeć Pol J Microbiol 2014; 63 (2): ICID: 1115557 Article type: Original article IC™ Value: 10.00
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In the past years, opportunistic fungal infections have seriously increased, mainly in immunocompromised patients. The aim of the study was to determine the prevalence of yeast-like fungi in systemic mycoses and to estimate its susceptibility to chosen antifungal agents. One hundred and sixty strains of yeast-like fungi were cultured from various clinical material: the samples from lower respiratory tracts, blood, and the peritoneal cavity and others. The susceptibility tests were established according to the quantitative E-test method. The Candida genus represented the main etiological factor of systemic mycoses. The predominant species were: C. glabrata (71/160), C. albicans (34/160), C. krusei (17/160), C. tropicalis (14/160). All tested strains were the most resistant to itraconazole. Candida glabrata presented the 100% susceptibility to amphotericin B and caspofungin and was the least susceptible to itraconazole, posaconazole and voriconazole. Candida albicans was the most susceptible species to all antymicotics.