Recombinant MAG1 Protein of Toxoplasma gondii as a Diagnostic Antigen

Justyna M. Gatkowska, Bożena Dziadek, Jarosław Dziadek, Katarzyna Dzitko, Henryka Długońska
Pol J Microbiol
2015; 64 (1):
ICID: 1148775
Article type: Short communication
IC™ Value: 6.00
Abstract provided by Publisher
The aim of this study was to evaluate the potential diagnostic usefulness of the full-length recombinant <em>Toxoplasma gondii</em> MAG1 protein by determining the levels of specific IgM and IgG antibodies in mouse and human sera obtained from individuals with acute and chronic toxoplasmosis. The obtained results revealed that IgG antibodies against MAG1 are a sensitive and specific marker of <em>T. gondii</em> infection since the protein was recognized by both mouse and human sera, 100% and 94.3%, respectively, rendering the full-length rMAG1 a prospective alternative for the polyvalent native antigen (TLA).

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