Chaperon DnaJ Influences the Formation of Biofilm in Escherichia coli

Anna M Grudniak, Jolanta Włodkowska, Krystyna I Wolska
Pol J Microbiol
2015; 64 (3):
ICID: 1170467
Article type: Short communication
IC™ Value: 6.00
Abstract provided by Publisher
 
DnaJ chaperone, a member of the so called DnaK-DnaJ-GrpE chaperone machine plays an important role in cell physiology. The ability of Escherichia coli ΔdnaJ mutant to form biofilm was studied. It was shown that this mutant is impaired in biofilm development when exposed to 42°C for 2 h. The impairment in biofilm development was observed when the heat shock was applied either at the onset of biofilm formation or 2 h later. The biofilm formed was thinner and its structure was changed as compared to wild-type strain. This defect could be complemented by the introduction of a wild-type gene on a low-copy plasmid.
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