Five Years’ Evaluation of BD ProbeTec system for the direct molecular detection of Mycobacterium tuberculosis complex in respiratory and nonrespiratory clinical samples
Can Bicmen, Onur Karaman, Ayriz T. Gunduz, Onur F. Erer, Meral Coskun, Osman Kaftan, Mahmut M. Demirel, Gunes Senol, Tulay Akarca, Sevket Dereli, Ayse Ozsoz Pol J Microbiol 2015; 64 (4): ICID: 1185240 Article type: Short communication IC™ Value: 6.00
Abstract provided by Publisher
In this study, Mycobacterium tuberculosis complex was detected by BD ProbeTec ET system in 4716 respiratory and 167 nonrespiratory samples [mostly (98%) smear negative]. Sensitivity, specificity, positive and negative predictive values were 81.8%, 98.3, 85.1 and 97.9 for respiratory and 100%, 96.2, 64.7 and 100, for nonrespiratory samples, respectively. Among 149 (3.1%) ProbeTec DTB positive and culture negative samples, 72 (65 respiratory and seven nonrespiratory) (48.3%) were recovered from the patients who were evaluated as having TB infection. The system has been found as useful in early diagnosis of tuberculosis infection in association with the clinical, radiological and histopathological findings.