Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus
Bogdan Minea, Valentin Nastasa, Anna Kolecka, Magdalena Mares, Narcisa Marangoci, Irina Rosca, Mariana Pinteala, Monica Hancianu, Mihai Mares Pol J Microbiol 2016; 65 (1): ICID: 1197327 Article type: Short communication IC™ Value: 6.00
Abstract provided by Publisher
This is the first Romanian investigation of oral candidosis in patients suffering of HIV-infection or type 1 diabetes mellitus (T1DM). Candida albicans was the dominant species in both types of isolates: n = 14 (46.7%) in T1DM, n = 60 (69.8%) in HIV. The most frequent non-albicans Candida spp. were Candida kefyr (n = 6; 20%) in T1DM and Candida dubliniensis (n = 8; 9.3%) in HIV. Resistance to fluconazole was detected only in the HIV non-albicans Candida group (n = 8; 9.3%). All isolates were susceptible to VOR. The experimental drug MXP had MIC values equal or close to the ones of VOR. Echinocandin resistance was more frequent than azole resistance.