From Latent Tuberculosis Infection to Tuberculosis. News in Diagnostics (QuantiFERON-Plus)

Dagmara I. Borkowska, Agnieszka M. Napiórkowska, Sylwia A. Brzezińska, Monika Kozińska, Anna T. Zabost, Ewa M. Augustynowicz-Kopeć
Pol J Microbiol
2017; 66 (1):
ICID: 1234987
Article type: Review article
IC™ Value: 8.00
Abstract provided by Publisher
 
It is estimated that one third of the world’s population have latent tuberculosis infection and that this is a significant reservoir for future tuberculosis cases. Most cases occur within two years following initial infection. The identification of individuals with latent tuberculosis infection is difficult due to the lack of an ideal diagnostic assay and incomplete understanding of latent infection. Currently, there are three tests: the oldest tuberculin skin test, T-SPOT.TB and the latest QuantiFERON-Plus for the detection of Mycobacterium tuberculosis infection. The interpretation of the test results must be used in the conjunction with a patient’s epidemiological history, risk assessment, current clinical status, radiography and microbiological methods to ensure accurate diagnosis.
DOI: 10.5604/17331331.1234987
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